PAT Techniques Demonstrated at APGI Workshop in France
On July 6th, 2017 Andrea Gelain, Freund-Vector’s Associate Process Scientist attended the APGI (Association de Pharmacie Galénique Industrielle) Workshop on Oral Controlled Release in Lille University (France). University delegates from all around the world were present and these delegates provide information on their Research &Development projects. This conference focused on modified release pharmaceutical dosage forms.
During the APGI workshop, Andrea Gelain presented two (2) scientific posters on Freund-Vector’s High Shear granulation technology and Top Spray granulation utilizing VIAVI’s Near-Infrared Reflectance (NIR). The use of near infrared (NIR) reflectance has rapidly grown partly due to demands of process analytical applications within the pharmaceutical industry. The non-invasive and non-dstructive nature of measurements makes NIR a powerful tool in analyzing pharmaceutical solids. NIR’s benefits include: increased process understanding, better process control and improved quality of drug products.
Poster 1: Top Spray Granulation PAT Monitoring by NIR: Calibration vs. PCA Trend Approach
Leveraging Freund-Vector’s fluid bed, VFC- Lab 3 with Viavi’s MicronNIR PAT U device, this poster will show the endpoint for Top Spray granulation and establish the correlation between moisture content and particle size distribution of mixture using NIR technology.
Poster 2: Drying PAT Monitoring by NIR: Calibration vs. PCA Trend Approach
Leveraging Freund-Vector’s high shear mixer, GMXB Pilot and Freund-Vector’s fluid bed, VFC- Lab 3 with Viavi’s MicronNIR PAT U device, this poster will show the endpoint for drying and establish correlation between moisture of the mixture using NIR technology.