Processing of Extended Release Tablets Containing Carbopol® 971P NF Polymer by Top-Drive High Shear

To evaluate the aqueous granulation process in a pilot-scale top-drive high shear granulator for guaifenesin formulations containing (10% or 20% w/w) Carbopol® 971P NF polymer and to determine the effect of processing conditions on the granule and tablet properties and on drug release.

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