The purpose of these study was to develop and introduce several novel processing methods which can be done with the GRANUREX® conical rotor technology. These methods include spherical granulation, powder layering, and solution/suspension coating.
The introduction of spray drying technology into a pharmaceutical manufacturing business can provide new opportunities for product line expansion, business growth, and channels to increase revenue and profits. This can be from creation of new products that cannot be produced any other way. But it can also allow for line extensions of existing products and alternate drug product solutions for known API’s already offered in the market today.
Tablets and capsules dispensed to companion animals are given via a ‘poke down’ method or hidden in an attractive food. Ideally, the tablet or capsule would be voluntarily consumed from the pet owner’s hand or the pet’s bowl, which means veterinary pharmaceutical companies strive to develop products with high palatability.
The GRANUREX® technology offers great flexibility to produce immediate or modified release pellets, granules, or multi-particulates with high API loading with high efficiency and at significantly lower processing times. Based on current processing data available, the process technology is capable to achieve >500% w/w weight gain and product yields of > 95% with high bulk density.